Over 3,000 doses of the Pfizer vaccine are expected to arrive in Prince Albert on Wednesday, according to the the province.
Administration of the 3,900 doses will follow soon after.
The province also reported that an additional nine residents who tested positive for COVID-19 have died.
The death of a resident in their 60s was reported in the central west zone. Two new deaths in the 80 and above age group were reported in the south east. Three new deaths were reported in Regina, two in the 80 and above age group and one resident who was in their 20s. Two deaths were reported in Saskatoon: one resident in their 60s and another resident in their 50s have died.
The province reported 277 new COVID-19 cases and 439 new recoveries.
There are 40 new cases in the north central zone, which includes Prince Albert.